Restless Leg Syndrome (RLS)

2007-05-01T10:17:00.000+01:00

This review is a pragmatic attempt to highlight recent research and some backround reading in RLS. It should not be considered exhaustive, simply a way of reviewing some of the major developments and current thinking in the area.

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Evidence-Based Reports

Bandolier has a comprehensive section on restless legs.
Pramipexole and Ropinirole for Restless Legs Syndrome. Northern and Yorkshire Drug and Therapeutics Centre. 2006
Pramipexole (Restless Legs Syndrome). Midlands Therapeutics Review and Advisory Committee, 2007
Ropinirole (Restless Legs Syndrome). Midlands Therapeutics Review and Advisory Committee, 2007
Gabapentin improved sensory and motor symptoms in the restless legs syndrome. Evidence-Based Medicine (Requires free registration), 2004
Ropinirole was an effective treatment for restless leg syndrome (RLS), but the magnitude of the effect was uncertain. Neurology CATs, 2004

Recent articles in core journals

Efficacy and safety of pramipexole in restless legs syndrome. Neurology, 2006
Efficacy of cabergoline in restless legs syndrome: a placebo-controlled study with polysomnography (CATOR). Neurology, 2006

eTextbooks

Clinical Queries

Is there any correlation between childhood growing pains and restless legs in later life? NLH Q&A Service, 2006
What is the role of magnesium in treating restless leg syndrome? ATTRACT, 2005
A lady with terrible restless legs and a low ferritin of 7.5 (ref range 12-230) but a normal Hb. is it worth putting her on iron? NLH Q&A Service, 2006. View answer OR Can you answer this question for extra CPD?

Patient information

TRIP Evidence Reviews: Restless Leg Syndrome

Restless Leg Syndrome (RLS)