This review is a pragmatic attempt to highlight recent research and some backround reading in RLS. It should not be considered exhaustive, simply a way of reviewing some of the major developments and current thinking in the area.
Click here to see all the TRIP Evidence Reviews.
Evidence-Based Reports- Bandolier has a comprehensive section on restless legs.
- Pramipexole and Ropinirole for Restless Legs Syndrome. Northern and Yorkshire Drug and Therapeutics Centre. 2006
- Pramipexole (Restless Legs Syndrome). Midlands Therapeutics Review and Advisory Committee, 2007
- Ropinirole (Restless Legs Syndrome). Midlands Therapeutics Review and Advisory Committee, 2007
- Gabapentin improved sensory and motor symptoms in the restless legs syndrome. Evidence-Based Medicine (Requires free registration), 2004
- Ropinirole was an effective treatment for restless leg syndrome (RLS), but the magnitude of the effect was uncertain. Neurology CATs, 2004
Recent articles in core journals
- Efficacy and safety of pramipexole in restless legs syndrome. Neurology, 2006
- Efficacy of cabergoline in restless legs syndrome: a placebo-controlled study with polysomnography (CATOR). Neurology, 2006
eTextbooks
Clinical Queries
- Is there any correlation between childhood growing pains and restless legs in later life? NLH Q&A Service, 2006
- What is the role of magnesium in treating restless leg syndrome? ATTRACT, 2005
- A lady with terrible restless legs and a low ferritin of 7.5 (ref range 12-230) but a normal Hb. is it worth putting her on iron? NLH Q&A Service, 2006. View answer OR Can you answer this question for extra CPD?
Patient information
